Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation

Purpose Alpha-melanocyte stimulating hormone (α-MSH) is known to have anti-inflammatory effects. However, the anti-inflammatory properties of α-MSH on normal bronchial epithelial cells are largely unknown, especially in the context of in vitro sarcoidosis models. Methods We evaluated the anti-inflam...

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Bibliographic Details
Published in:	Lung Vol. 200; no. 4; pp. 463 - 472
Main Authors:	Shahraki, Abdolrazagh Hashemi, Tian, Runxia, Zhang, Chongxu, Fregien, Nevis L., Bejarano, Pablo, Mirsaeidi, Mehdi
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.08.2022 Springer Springer Nature B.V
Subjects:	a-Melanocyte-stimulating hormone alpha-MSH - metabolism alpha-MSH - pharmacology alpha-MSH - therapeutic use Animal models Animals Anti-inflammatory agents Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Anti-inflammatory drugs Biochips Biological response modifiers Chemical compounds Cytokines Cytotoxicity Epithelial cells Epithelium Granuloma - drug therapy Granulomas In vitro methods and tests Inflammation Inflammation - metabolism Interferon Intermedin Lungs Lymphocytes T Macrophages Medicine Medicine & Public Health Melanocyte-stimulating hormone Mice Pathogenesis Pharmacology Pneumology/Respiratory System Sarcoidosis Sarcoidosis - drug therapy Sarcoidosis, Pulmonary - drug therapy T cells Three dimensional models In vitro granuloma model Bronchial epithelial cells Type I interferons Sarcoidosis α-MSH Mice model
ISSN:	0341-2040, 1432-1750, 1432-1750
Online Access:	Get full text
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