ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

The advent of single-cell chromatin accessibility profiling has accelerated the ability to map gene regulatory landscapes but has outpaced the development of scalable software to rapidly extract biological meaning from these data. Here we present a software suite for single-cell analysis of regulato...

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Veröffentlicht in:	Nature genetics Jg. 53; H. 3; S. 403 - 411
Hauptverfasser:	Granja, Jeffrey M., Corces, M. Ryan, Pierce, Sarah E., Bagdatli, S. Tansu, Choudhry, Hani, Chang, Howard Y., Greenleaf, William J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Nature Publishing Group US 01.03.2021 Nature Publishing Group
Schlagworte:	38/22 38/23 38/39 45 631/208/176 631/208/177 631/208/200 Accessibility Agriculture Animal Genetics and Genomics Animals Biomedical and Life Sciences Biomedicine Cancer Research Chromatin Chromatin - genetics Chromatin - metabolism Cluster Analysis Clustering Computer programs Datasets Deoxyribonucleic acid DNA Electronic data processing Footprinting Gene expression Gene Expression Regulation Gene Function Gene regulation Gene sequencing Genetic regulation Genetic research Genome Genomics Human Genetics Humans Identification Mice Science Sequence Analysis, RNA - methods Single-Cell Analysis - methods Software Software packages technical-report Technology application Transcription factors Transcription Factors - genetics Transcription Factors - metabolism UNIX User-Computer Interface Web Browser United States
ISSN:	1061-4036, 1546-1718, 1546-1718
Online-Zugang:	Volltext
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