A molecular cell atlas of the human lung from single-cell RNA sequencing

Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 – 9 , it has been difficult to systematically identify and localize all molecular cell types in individual organs to create a full molecular cell atlas. Here, using d...

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Veröffentlicht in:	Nature (London) Jg. 587; H. 7835; S. 619 - 625
Hauptverfasser:	Travaglini, Kyle J., Nabhan, Ahmad N., Penland, Lolita, Sinha, Rahul, Gillich, Astrid, Sit, Rene V., Chang, Stephen, Conley, Stephanie D., Mori, Yasuo, Seita, Jun, Berry, Gerald J., Shrager, Joseph B., Metzger, Ross J., Kuo, Christin S., Neff, Norma, Weissman, Irving L., Quake, Stephen R., Krasnow, Mark A.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 26.11.2020 Nature Publishing Group
Schlagworte:	13/1 13/31 13/51 14/1 14/19 14/32 38/32 38/39 38/77 38/91 631/181/2474 631/208/199 631/208/212/2019 631/337/2019 64/110 64/60 82/1 Aged Analysis Animals Annotations Atlases as Topic Biomarkers Blood Blood circulation Cell Communication Cell cycle Cells Cells - classification Cells - immunology Cells - metabolism Chemokines - metabolism Endothelial Cells - metabolism Epithelial Cells - metabolism Evolution Female Fibroblasts Gene expression Gene sequencing Genomes Hormones Humanities and Social Sciences Humans Identification and classification Immune system Immunity Lung - cytology Lung - immunology Lung diseases Lungs Male Methods Mice Middle Aged Molecular biology multidisciplinary Organs Physiological aspects Quorum sensing Receptors, Lymphocyte Homing - metabolism Ribonucleic acid RNA RNA sequencing Science Science (multidisciplinary) Sequence Analysis, RNA Signal Transduction Single-Cell Analysis Stromal Cells - metabolism Switches Tissue engineering Transcription factors Transcriptome - genetics United States
ISSN:	0028-0836, 1476-4687, 1476-4687
Online-Zugang:	Volltext
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