Biomarkers of inflammation and repair in kidney disease progression

INTRODUCTIONAcute kidney injury and chronic kidney disease (CKD) are common in hospitalized patients. To inform clinical decision making, more accurate information regarding risk of long-term progression to kidney failure is required.METHODSWe enrolled 1538 hospitalized patients in a multicenter, pr...

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Bibliographic Details
Published in:	The Journal of clinical investigation Vol. 131; no. 3; pp. 1 - 10
Main Authors:	Puthumana, Jeremy, Thiessen-Philbrook, Heather, Xu, Leyuan, Coca, Steven G., Garg, Amit X., Himmelfarb, Jonathan, Bhatraju, Pavan K., Ikizler, T. Alp, Siew, Edward D., Ware, Lorraine B., Liu, Kathleen D., Go, Alan S., Kaufman, James S., Kimmel, Paul L., Chinchilli, Vernon M., Cantley, Lloyd G., Parikh, Chirag R.
Format:	Journal Article
Language:	English
Published:	United States American Society for Clinical Investigation 01.02.2021
Subjects:	Acute Kidney Injury - urine Acute phase reaction Acute renal failure Aged Animal models Animals Atrophy Biological markers Biomarkers Biomarkers - urine Biomedical research Chemokine CCL2 - urine Chitinase-3-Like Protein 1 - urine Clinical decision making Clinical Medicine Decision making Development and progression Disease Models, Animal Disease Progression End-stage renal disease Epidermal growth factor receptors Female Fibrosis Follow-Up Studies Gene expression Glomerular Filtration Rate Health aspects Hospitalization Humans Inflammation Inflammation - urine Kidney diseases Leukocytes (neutrophilic) Loop of Henle Macrophages Male Mice Middle Aged Monocyte chemoattractant protein Monocyte chemoattractant protein 1 Monocytes Mortality Patients Physiological aspects Prognosis Reclassification Renal failure Renal Insufficiency, Chronic - urine Urine United States Nephrology Chronic kidney disease Inflammation Molecular diagnosis Clinical practice
ISSN:	0021-9738, 1558-8238, 1558-8238
Online Access:	Get full text
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