Eight-gene metabolic signature related with tumor-associated macrophages predicting overall survival for hepatocellular carcinoma

Background In recent years, the relationship between tumor-associated macrophages (TAMs) and solid tumors has become a research hotspot. This study aims to explore the close relationship of TAMs with metabolic reprogramming genes in hepatocellular carcinoma (HCC) to provide new methods of treatment...

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Vydané v:	BMC cancer Ročník 21; číslo 1; s. 31 - 15
Hlavní autori:	Huo, Junyu, Wu, Liqun, Zang, Yunjin, Dong, Hongjing, Liu, Xiaoqiang, He, Fu, Zhang, Xiao
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 07.01.2021 BioMed Central Ltd Springer Nature B.V BMC
Predmet:	Abundance Aged Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Cellular Reprogramming - genetics Correlation analysis CTLA-4 protein Datasets Female Follow-Up Studies Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic aspects Genetics Genomes genomics and epigenetics Health aspects Health Promotion and Disease Prevention Hepatocellular carcinoma Hepatoma Humans Immune checkpoint Liver cancer Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - mortality Liver Neoplasms - pathology Macrophages Male Medical prognosis Medicine/Public Health Metabolic Metabolic regulation Metabolism Metabolites Metastases Metastasis Oncology Patients PD-1 protein Prognosis Prognostic Regression analysis Research Article Risk groups Signature Solid tumors Surgical Oncology Survival analysis Survival Rate Tumor-associated macrophages Tumor-Associated Macrophages - metabolism Tumor-Associated Macrophages - pathology Tumors China Hepatocellular carcinoma Metabolic Tumor-associated macrophages Prognostic Signature
ISSN:	1471-2407, 1471-2407
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