Brain regional lesion burden and impaired mobility in the elderly

This study investigated the relationship of brain white matter (WM) lesions affecting specific neural networks with decreased mobility in ninety-nine healthy community-dwelling subjects ≥75 years old prospectively enrolled by age and mobility status. We assessed lesion burden in the genu, body and s...

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Bibliographic Details
Published in:	Neurobiology of aging Vol. 32; no. 4; pp. 646 - 654
Main Authors:	Moscufo, Nicola, Guttmann, Charles R.G., Meier, Dominik, Csapo, Istvan, Hildenbrand, Peter G., Healy, Brian C., Schmidt, Julia A., Wolfson, Leslie
Format:	Journal Article
Language:	English
Published:	London Elsevier Inc 01.04.2011 Elsevier
Subjects:	Aged Aged, 80 and over Aging Aging - pathology Aging - physiology Biological and medical sciences Brain Brain - pathology Corona radiata Development. Senescence. Regeneration. Transplantation Female Fundamental and applied biological sciences. Psychology Gait - physiology Humans Image Processing, Computer-Assisted Internal Medicine Logistic Models Magnetic Resonance Imaging Male Mobility Nerve Fibers, Myelinated - pathology Neurology Prospective Studies Splenium of corpus callosum Vertebrates: nervous system and sense organs Walking - physiology White matter White matter hyperintensity Brain White matter hyperintensity Magnetic resonance imaging Splenium of corpus callosum Corona radiata Aging Mobility White matter Senescence Central nervous system Nuclear magnetic resonance imaging Corpus callosum Encephalon Lesion
ISSN:	0197-4580, 1558-1497, 1558-1497
Online Access:	Get full text
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