Synthetic carbohydrate-based vaccines: challenges and opportunities

Glycoconjugate vaccines based on bacterial capsular polysaccharides (CPS) have been extremely successful in preventing bacterial infections. The glycan antigens for the preparation of CPS based glycoconjugate vaccines are mainly obtained from bacterial fermentation, the quality and length of glycans...

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Bibliographic Details
Published in:	Journal of biomedical science Vol. 27; no. 1; pp. 9 - 22
Main Authors:	Mettu, Ravinder, Chen, Chiang-Yun, Wu, Chung-Yi
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.01.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Antibiotics Antigenicity Antigens Antimicrobial agents Bacteria Bacterial diseases Bacterial infections Bacterial vaccines Biomedical and Life Sciences Biomedicine Cancer Capsular polysaccharides Carbohydrates Chemical synthesis Chemistry Clinical trials Fermentation Glycan Health aspects Immunogenicity Infection Licenses Medical research Pathogens Pneumonia Polysaccharides Proteins Researchers Review Saccharides Salmonella Streptococcus infections Success Translating innovative biomedical research in disease treatments Vaccines Vaccines and Cancer United States > US Carbohydrates Polysaccharides Immunogenicity Antigenicity Vaccines and Cancer
ISSN:	1423-0127, 1021-7770, 1423-0127
Online Access:	Get full text
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