Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims

Teenage suicide is a major public health concern, but its neurobiology is not well understood. Proinflammatory cytokines play an important role in stress and in the pathophysiology of depression—two major risk factors for suicide. Cytokines are increased in the serum of patients with depression and...

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Bibliographic Details
Published in:	Journal of psychiatric research Vol. 46; no. 1; pp. 57 - 63
Main Authors:	Pandey, Ghanshyam N., Rizavi, Hooriyah S., Ren, Xinguo, Fareed, Jawed, Hoppensteadt, Debra A., Roberts, Rosalinda C., Conley, Robert R., Dwivedi, Yogesh
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 01.01.2012 Elsevier
Subjects:	Adolescent Adult and adolescent clinical studies Biological and medical sciences Child Cortex Cytokines Cytokines - genetics Cytokines - metabolism Enzyme-Linked Immunosorbent Assay Female Gene Expression Regulation - physiology Humans IL-1β IL-6 Male Medical sciences Pathophysiological aspects Postmortem brain Postmortem Changes Prefrontal Cortex - metabolism Prefrontal Cortex - pathology Proteins Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry RNA, Messenger - metabolism Suicidal behaviour Suicide Teenage suicide TNF-α Victims Young Adult Teenage suicide Cytokines TNF-α IL-1β Postmortem brain IL-6 Central nervous system Cytokine Postmortem Interleukin 1β Inflammation Prefrontal cortex Suicide Encephalon Interleukin 6 Tumor necrosis factor α Victim
ISSN:	0022-3956, 1879-1379, 1879-1379
Online Access:	Get full text
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