Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)

In April 2008, a nucleotide-sequence-based, complete genome classification system was developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of the 11 genome segments of a particular RV strain according to established nucleotide percent cutoff values. Using this app...

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Bibliographic Details
Published in:Archives of virology Vol. 156; no. 8; pp. 1397 - 1413
Main Authors: Matthijnssens, Jelle, Ciarlet, Max, McDonald, Sarah M., Attoui, Houssam, Bányai, Krisztián, Brister, J. Rodney, Buesa, Javier, Esona, Mathew D., Estes, Mary K., Gentsch, Jon R., Iturriza-Gómara, Miren, Johne, Reimar, Kirkwood, Carl D., Martella, Vito, Mertens, Peter P. C., Nakagomi, Osamu, Parreño, Viviana, Rahman, Mustafizur, Ruggeri, Franco M., Saif, Linda J., Santos, Norma, Steyer, Andrej, Taniguchi, Koki, Patton, John T., Desselberger, Ulrich, Van Ranst, Marc
Format: Journal Article
Language:English
Published: Vienna Springer Vienna 01.08.2011
Springer
Springer Nature B.V
Springer Verlag
Subjects:
Animals
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
chickens
Chiroptera
classification
common names
conception
cows
Fundamental and applied biological sciences. Psychology
genes
genetics
Genome, Viral
Genomes
Genotype
horses
Humans
Immunology
Infections
Infectious Diseases
Lama guanicoe
Life Sciences
Medical Microbiology
Medical research
Medicine
mice
Microbiology
Miscellaneous
National Center for Biotechnology Information
nucleotide sequences
Original Article
Phasianidae
pheasants
Proteins
Public health
R&D
Research & development
RNA polymerase
Rotavirus
Rotavirus - classification
Rotavirus - genetics
Species Specificity
sugars
swine
Terminology as Topic
turkeys
Virology
Viruses
Working groups
Brazil
Rio de Janeiro Brazil
Ohio
United Kingdom > UK
United States > US
Genome Segment
Nomenclature System
Equivalent Mechanism
Vaccine Strain
Reverse Genetic
Virus
Rotavirus
Nomenclature
Reoviridae
Strain
ISSN:0304-8608, 1432-8798, 1432-8798
Online Access:Get full text
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Summary:In April 2008, a nucleotide-sequence-based, complete genome classification system was developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of the 11 genome segments of a particular RV strain according to established nucleotide percent cutoff values. Using this approach, the genome of individual RV strains are given the complete descriptor of Gx-P[x]-Ix-Rx-Cx-Mx-Ax-Nx-Tx-Ex-Hx. The Rotavirus Classification Working Group (RCWG) was formed by scientists in the field to maintain, evaluate and develop the RV genotype classification system, in particular to aid in the designation of new genotypes. Since its conception, the group has ratified 51 new genotypes: as of April 2011, new genotypes for VP7 (G20-G27), VP4 (P[28]-P[35]), VP6 (I12-I16), VP1 (R5-R9), VP2 (C6-C9), VP3 (M7-M8), NSP1 (A15-A16), NSP2 (N6-N9), NSP3 (T8-T12), NSP4 (E12-E14) and NSP5/6 (H7-H11) have been defined for RV strains recovered from humans, cows, pigs, horses, mice, South American camelids (guanaco), chickens, turkeys, pheasants, bats and a sugar glider. With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification/G- and P-type. In collaboration with the National Center for Biotechnology Information (NCBI), the RCWG is also working on developing a RV-specific resource for the deposition of nucleotide sequences. This resource will provide useful information regarding RV strains, including, but not limited to, the individual gene genotypes and epidemiological and clinical information. Together, the proposed nomenclature system and the NCBI RV resource will offer highly useful tools for investigators to search for, retrieve, and analyze the ever-growing volume of RV genomic data.
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ISSN:0304-8608
1432-8798
1432-8798
DOI:10.1007/s00705-011-1006-z