High Differentiation among Eight Villages in a Secluded Area of Sardinia Revealed by Genome-Wide High Density SNPs Analysis

To better design association studies for complex traits in isolated populations it's important to understand how history and isolation moulded the genetic features of different communities. Population isolates should not "a priori" be considered homogeneous, even if the communities ar...

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Veröffentlicht in:	PloS one Jg. 4; H. 2; S. e4654
Hauptverfasser:	Pistis, Giorgio, Piras, Ignazio, Pirastu, Nicola, Persico, Ivana, Sassu, Alessandro, Picciau, Andrea, Prodi, Dionigio, Fraumene, Cristina, Mocci, Evelina, Manias, Maria Teresa, Atzeni, Rossano, Cosso, Massimiliano, Pirastu, Mario, Angius, Andrea
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 27.02.2009 Public Library of Science (PLoS)
Schlagworte:	Analysis Baldness Cardiovascular disease Communities Correlation analysis Design optimization Differentiation Extreme values Genetics and Genomics Genetics and Genomics/Complex Traits Genetics and Genomics/Population Genetics Genetics, Population Genome, Human Genomes Genomics Geography Heart attacks Humans Immigration Italy Life sciences Linkage Disequilibrium Lupus Polymorphism, Single Nucleotide Population Population density Population genetics Population number Population structure Populations Rheumatoid arthritis Rural Population Single-nucleotide polymorphism Structural analysis Studies Uric acid Villages Italy Finland
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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