High Differentiation among Eight Villages in a Secluded Area of Sardinia Revealed by Genome-Wide High Density SNPs Analysis

To better design association studies for complex traits in isolated populations it's important to understand how history and isolation moulded the genetic features of different communities. Population isolates should not "a priori" be considered homogeneous, even if the communities ar...

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Vydáno v:	PloS one Ročník 4; číslo 2; s. e4654
Hlavní autoři:	Pistis, Giorgio, Piras, Ignazio, Pirastu, Nicola, Persico, Ivana, Sassu, Alessandro, Picciau, Andrea, Prodi, Dionigio, Fraumene, Cristina, Mocci, Evelina, Manias, Maria Teresa, Atzeni, Rossano, Cosso, Massimiliano, Pirastu, Mario, Angius, Andrea
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 27.02.2009 Public Library of Science (PLoS)
Témata:	Analysis Baldness Cardiovascular disease Communities Correlation analysis Design optimization Differentiation Extreme values Genetics and Genomics Genetics and Genomics/Complex Traits Genetics and Genomics/Population Genetics Genetics, Population Genome, Human Genomes Genomics Geography Heart attacks Humans Immigration Italy Life sciences Linkage Disequilibrium Lupus Polymorphism, Single Nucleotide Population Population density Population genetics Population number Population structure Populations Rheumatoid arthritis Rural Population Single-nucleotide polymorphism Structural analysis Studies Uric acid Villages Italy Finland
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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