Credibility assessment of in silico clinical trials for medical devices

In silico clinical trials (ISCTs) are an emerging method in modeling and simulation where medical interventions are evaluated using computational models of patients. ISCTs have the potential to provide cost-effective, time-efficient, and ethically favorable alternatives for evaluating the safety and...

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Vydané v:	PLoS computational biology Ročník 20; číslo 8; s. e1012289
Hlavní autori:	Pathmanathan, Pras, Aycock, Kenneth, Badal, Andreu, Bighamian, Ramin, Bodner, Jeff, Craven, Brent A., Niederer, Steven
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Public Library of Science 01.08.2024 Public Library of Science (PLoS)
Predmet:	Biology and Life Sciences Clinical trials Clinical Trials as Topic - methods Clinical Trials as Topic - standards Computer and Information Sciences Computer Simulation - standards Credibility Effectiveness Engineering and Technology Equipment and Supplies - adverse effects Equipment and Supplies - standards Ethical aspects Evaluation Human subjects Intervention Machine learning Mathematical models Medical devices Medical equipment Medical imaging equipment Medical technology Medicine and Health Sciences Patients Physiological apparatus Physiology Product development Reproducibility of Results Research and Analysis Methods Simulation Simulation methods Testing Workflow United States
ISSN:	1553-7358, 1553-734X, 1553-7358
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