A pH-Driven and photoresponsive nanocarrier: Remotely-controlled by near-infrared light for stepwise antitumor treatment

The hollow gold nanospheres (HAuNS) have shown medicinal promise due to their inert and nontoxic properties with unique photothermal therapy capabilities. In this study, the electrostatic approach was employed to successfully absorb Chlorin e6 (Ce6) simultaneously with the pH (low) insertion peptide...

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Bibliographic Details
Published in:	Biomaterials Vol. 79; pp. 25 - 35
Main Authors:	Yu, Meng, Guo, Fang, Wang, Jinping, Tan, Fengping, Li, Nan
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.02.2016
Subjects:	Ablation absorption Advanced Basic Science Cell Survival - drug effects Cell Survival - radiation effects chlorins Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - chemistry Delayed-Action Preparations - radiation effects Delivery systems Dentistry Diffusion - radiation effects electrostatic interactions Electrostatics fever gold Gold - chemistry Gold - therapeutic use HeLa Cells Humans Hydrogen-Ion Concentration Insertion irradiation ligands Metal Nanoparticles - chemistry Metal Nanoparticles - therapeutic use Nanocapsules - administration & dosage Nanocapsules - chemistry Nanocapsules - radiation effects nanocarriers nanogold nanospheres Nanostructure neoplasm cells Patients Peptides pH-driven photochemotherapy Photochemotherapy - methods Photoresponsive photosensitizing agents Photosensitizing Agents - administration & dosage Porphyrins - administration & dosage PTT/PDT effect Single light trigger Stepwise therapy Therapy Treatment Outcome Photoresponsive Single light trigger pH-driven PTT/PDT effect Stepwise therapy
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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