Targeting apoptosis pathways by natural compounds in cancer: Marine compounds as lead structures and chemical tools for cancer therapy

Natural compounds derived from marine organisms have shown a wide variety of anti-tumor effects and a lot of attention has been drawn to further development of the isolated compounds. A vast quantity of individual chemical structures from different organisms has shown a variety of apoptosis inducing...

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Bibliographic Details
Published in:	Cancer letters Vol. 332; no. 2; pp. 295 - 303
Main Authors:	von Schwarzenberg, Karin, Vollmar, Angelika M.
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 28.05.2013 Elsevier Limited
Subjects:	Alkaloids Alkaloids - pharmacology Alkanes Alkanes - pharmacology Animals Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology Antineoplastic Agents Antineoplastic Agents - pharmacology Apoptosis Aquatic Organisms Aquatic Organisms - chemistry Biological Products Biological Products - pharmacology Bryostatins Bryostatins - pharmacology Cancer Cancer therapies Carbamates Carbamates - pharmacology caspases cell growth Cell Proliferation chemical structure chemistry Depsipeptides Depsipeptides - pharmacology Dioxoles Dioxoles - pharmacology Drug Screening Assays, Antitumor Hematology, Oncology and Palliative Medicine Humans Kinases Lactones Lactones - pharmacology Macrolides Macrolides - pharmacology Marine compounds mechanism of action metabolism Microtubules Microtubules - metabolism Models, Chemical Natural compounds Neoplasms Neoplasms - metabolism Neoplasms - pathology pathology pharmacology Phenanthrolines Phenanthrolines - pharmacology Phenazines Phenazines - pharmacology proteasome endopeptidase complex Proteasome Endopeptidase Complex - metabolism Pyrones Pyrones - pharmacology Pyrroles Pyrroles - pharmacology Quinolines Quinolines - pharmacology Spiro Compounds Spiro Compounds - pharmacology Steroids Steroids - pharmacology Tetrahydroisoquinolines Tetrahydroisoquinolines - pharmacology therapeutics Thiazoles Thiazoles - pharmacology Trabectedin Natural compounds Marine compounds Cancer Apoptosis
ISSN:	0304-3835, 1872-7980, 1872-7980
Online Access:	Get full text
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