Reversal of anticoagulant effects of edoxaban, an oral, direct factor Xa inhibitor, with haemostatic agents

Edoxaban, an oral, direct factor Xa inhibitor, has a similar or low incidence of bleeding events compared with other anticoagulants in clinical trials. Therefore, agents to reverse the anticoagulant effects of edoxaban could be desirable in emergency situations. In this study, the reversal effects o...

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Bibliographic Details
Published in:	Thrombosis and haemostasis Vol. 107; no. 2; p. 253
Main Authors:	Fukuda, Toshio, Honda, Yuko, Kamisato, Chikako, Morishima, Yoshiyuki, Shibano, Toshiro
Format:	Journal Article
Language:	English
Published:	Germany 01.02.2012
Subjects:	Administration, Oral Animals Anticoagulants - administration & dosage Blood Coagulation Factors - administration & dosage Factor VIIa - administration & dosage Factor Xa Inhibitors Hemorrhage - etiology Hemorrhage - prevention & control Hemostasis - drug effects Humans Male Prothrombin Time Pyridines - administration & dosage Rats Rats, Inbred Strains Thiazoles - administration & dosage
ISSN:	0340-6245, 2567-689X, 2567-689X
Online Access:	Get more information
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