Clonal Hematopoiesis of Indeterminate Potential Predicts Adverse Outcomes in Patients With Atherosclerotic Cardiovascular Disease

Clonal hematopoiesis of indeterminate potential (CHIP)-the age-related clonal expansion of blood stem cells with leukemia-associated mutations-is a novel cardiovascular risk factor. Whether CHIP remains prognostic in individuals with established atherosclerotic cardiovascular disease (ASCVD) is less...

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Veröffentlicht in:	Journal of the American College of Cardiology Jg. 81; H. 20; S. 1996
Hauptverfasser:	Gumuser, Esra D, Schuermans, Art, Cho, So Mi Jemma, Sporn, Zachary A, Uddin, Md Mesbah, Paruchuri, Kaavya, Nakao, Tetsushi, Yu, Zhi, Haidermota, Sara, Hornsby, Whitney, Weeks, Lachelle D, Niroula, Abhishek, Jaiswal, Siddhartha, Libby, Peter, Ebert, Benjamin L, Bick, Alexander G, Natarajan, Pradeep, Honigberg, Michael C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 23.05.2023
Schlagworte:	Atherosclerosis - genetics Cardiovascular Diseases - epidemiology Cardiovascular Diseases - genetics Clonal Hematopoiesis - genetics Hematopoiesis - genetics Humans Middle Aged Mutation Splicing Factor U2AF - genetics coronary artery disease aging inflammation risk factor prevention
ISSN:	1558-3597, 1558-3597
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