Non-invasive in vivo measurement of the shear modulus of human vocal fold tissue

Voice is the essential part of singing and speech communication. Voice disorders significantly affect the quality of life. The viscoelastic mechanical properties of the vocal fold mucosa determine the characteristics of the vocal folds oscillations, and thereby voice quality. In the present study, a...

Celý popis

Uložené v:
Podrobná bibliografia
Vydané v:Journal of biomechanics Ročník 47; číslo 5; s. 1173 - 1179
Hlavní autori: Kazemirad, Siavash, Bakhshaee, Hani, Mongeau, Luc, Kost, Karen
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States Elsevier Ltd 21.03.2014
Predmet:
Adult
Algorithms
Biomedical materials
Elasticity
Female
High-speed imaging
Humans
In vivo tests
Magnetic Resonance Imaging
Male
Mathematical analysis
Mucosal wave propagation
Non-invasive measurement
Phonation
Physical Medicine and Rehabilitation
Shear modulus
Surgical implants
Vocal Cords - physiology
Voice
Wave propagation
Young Adult
Shear modulus
Mucosal wave propagation
High-speed imaging
Non-invasive measurement
ISSN:0021-9290, 1873-2380, 1873-2380
On-line prístup:Získať plný text
Tagy: Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
Popis
Shrnutí:Voice is the essential part of singing and speech communication. Voice disorders significantly affect the quality of life. The viscoelastic mechanical properties of the vocal fold mucosa determine the characteristics of the vocal folds oscillations, and thereby voice quality. In the present study, a non-invasive method was developed to determine the shear modulus of human vocal fold tissue in vivo via measurements of the mucosal wave propagation speed during phonation. Images of four human subjects' vocal folds were captured using high speed digital imaging (HSDI) and magnetic resonance imaging (MRI) for different phonation pitches, specifically fundamental frequencies between 110 and 440Hz. The MRI images were used to obtain the morphometric dimensions of each subject's vocal folds in order to determine the pixel size in the high-speed images. The mucosal wave propagation speed was determined for each subject and at each pitch value using an automated image processing algorithm. The transverse shear modulus of the vocal fold mucosa was then calculated from a surface (Rayleigh) wave propagation dispersion equation using the measured wave speeds. It was found that the mucosal wave propagation speed and therefore the shear modulus of the vocal fold tissue were generally greater at higher pitches. The results were in good agreement with those from other studies obtained via in vitro measurements, thereby supporting the validity of the proposed measurement method. This method offers the potential for in vivo clinical assessments of vocal folds viscoelasticity from HSDI.
Bibliografia:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:0021-9290
1873-2380
1873-2380
DOI:10.1016/j.jbiomech.2013.11.034