The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology

The synthetic biology research community describes a standard language for exchanging designs of biological 'parts'. The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synt...

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Veröffentlicht in:Nature biotechnology Jg. 32; H. 6; S. 545 - 550
Hauptverfasser: Galdzicki, Michal, Clancy, Kevin P, Oberortner, Ernst, Pocock, Matthew, Quinn, Jacqueline Y, Rodriguez, Cesar A, Roehner, Nicholas, Wilson, Mandy L, Adam, Laura, Anderson, J Christopher, Bartley, Bryan A, Beal, Jacob, Chandran, Deepak, Chen, Joanna, Densmore, Douglas, Endy, Drew, Grünberg, Raik, Hallinan, Jennifer, Hillson, Nathan J, Johnson, Jeffrey D, Kuchinsky, Allan, Lux, Matthew, Misirli, Goksel, Peccoud, Jean, Plahar, Hector A, Sirin, Evren, Stan, Guy-Bart, Villalobos, Alan, Wipat, Anil, Gennari, John H, Myers, Chris J, Sauro, Herbert M
Format: Journal Article
Sprache:Englisch
Veröffentlicht: New York Nature Publishing Group US 01.06.2014
Nature Publishing Group
Schlagworte:
631/114/2416
Agriculture
Bioinformatics
Biological research
Biology, Experimental
Biomedical Engineering/Biotechnology
Biomedicine
Biotechnology
Communication in science
Documentation
Information Dissemination - methods
Internationality
Life Sciences
perspective
Reference Standards
Research Design - standards
Software - standards
Synthetic biology
Synthetic Biology - standards
Terminology as Topic
Vocabulary, Controlled
ISSN:1087-0156, 1546-1696, 1546-1696
Online-Zugang:Volltext
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Zusammenfassung:The synthetic biology research community describes a standard language for exchanging designs of biological 'parts'. The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.
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ISSN:1087-0156
1546-1696
1546-1696
DOI:10.1038/nbt.2891