Autoantibody against the amino acid sequence 661–680 in apo B-100 is associated with decreased carotid stenosis and cardiovascular events

Immunization with malondialdehyde (MDA)-modified peptides corresponding to the amino acid sequence between 661 and 680 in apo B-100 (p45) inhibits atherosclerosis in apo E knockout mice. The same effect can be obtained by treating the mice with recombinant anti-MDA-p45 IgG, suggesting that these ant...

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Veröffentlicht in:	Atherosclerosis Jg. 194; H. 2; S. e188 - e192
Hauptverfasser:	Fredrikson, Gunilla Nordin, Schiopu, Alexandru, Berglund, Göran, Alm, Ragnar, Shah, Prediman K., Nilsson, Jan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Ireland Elsevier Ireland Ltd 01.10.2007
Schlagworte:	Aged Antibodies Apolipoprotein B-100 - genetics Apolipoprotein B-100 - immunology Apolipoproteins Autoantibodies - blood Autoantibodies - immunology Cardiology and Cardiovascular Disease Cardiovascular Carotid stenosis Case-Control Studies Clinical Medicine Cohort Studies Death, Sudden, Cardiac Female Humans Immunoglobulin G - blood Kardiologi och kardiovaskulära sjukdomar Klinisk medicin Male Medical and Health Sciences Medicin och hälsovetenskap Middle Aged Myocardial Infarction - immunology Peptide Peptide Fragments - immunology Peptides - immunology Risk Factors Ultrasound Carotid stenosis Antibodies Apolipoproteins Peptide Ultrasound
ISSN:	0021-9150, 1879-1484, 1879-1484
Online-Zugang:	Volltext
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