Complement pathway activation mediates pancreatic cancer–induced muscle wasting and pathological remodeling

Cancer cachexia is a multifactorial condition characterized by skeletal muscle wasting that impairs quality of life and longevity for many cancer patients. A greater understanding of the molecular etiology of this condition is needed for effective therapies to be developed. We performed a quantitati...

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Veröffentlicht in:The Journal of clinical investigation Jg. 135; H. 12
Hauptverfasser: D’Lugos, Andrew C., Ducharme, Jeremy B., Callaway, Chandler S., Trevino, Jose G., Atkinson, Carl, Judge, Sarah M., Judge, Andrew R.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States American Society for Clinical Investigation 30.06.2025
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ISSN:1558-8238, 0021-9738, 1558-8238
Online-Zugang:Volltext
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