Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

Maternal obesity is associated with increased birthweight, and obesity and premature mortality in adult offspring. The mechanism by which maternal obesity leads to these outcomes is not well understood, but maternal hyperglycaemia and insulin resistance are both implicated. We aimed to establish whe...

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Vydáno v:	The lancet. Diabetes & endocrinology Ročník 3; číslo 10; s. 778
Hlavní autoři:	Chiswick, Carolyn, Reynolds, Rebecca M, Denison, Fiona, Drake, Amanda J, Forbes, Shareen, Newby, David E, Walker, Brian R, Quenby, Siobhan, Wray, Susan, Weeks, Andrew, Lashen, Hany, Rodriguez, Aryelly, Murray, Gordon, Whyte, Sonia, Norman, Jane E
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.10.2015
Témata:	Abortion, Spontaneous - epidemiology Adult Diabetes, Gestational - epidemiology Double-Blind Method Female Fetal Macrosomia - epidemiology Humans Hypoglycemic Agents - therapeutic use Metformin - therapeutic use Obesity, Abdominal - drug therapy Pregnancy Pregnancy Complications - drug therapy Pregnancy Outcome - epidemiology Stillbirth - epidemiology Young Adult
ISSN:	2213-8595, 2213-8595
On-line přístup:	Zjistit podrobnosti o přístupu
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