Bik promotes proteasomal degradation to control low-grade inflammation

Although chronic low-grade inflammation does not cause immediate clinical symptoms, over the longer term, it can enhance other insults or age-dependent damage to organ systems and thereby contribute to age-related disorders, such as respiratory disorders, heart disease, metabolic disorders, autoimmu...

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Vydáno v:	The Journal of clinical investigation Ročník 134; číslo 4
Hlavní autoři:	Mebratu, Yohannes A., Jones, Jane T., Liu, Congjian, Negasi, Zerihun H., Rahman, Mizanur, Rojas-Quintero, Joselyn, O’Connor, George T., Gao, Wei, Dupuis, Josée, Cho, Michael H., Litonjua, Augusto A., Randell, Scott, Tesfaigzi, Yohannes
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States American Society for Clinical Investigation 15.02.2024
Témata:	Allergic reaction Allergy Animals Apoptosis Apoptosis Regulatory Proteins Apoptotic proteins Autoimmunity Development and progression Diseases Emphysema Emphysema, Pulmonary Female Genetic aspects Genetic engineering Health aspects Heart diseases Hexosyltransferases Humans Inflammation Inflammation - genetics Male Massachusetts Mice Mitochondrial Proteins New Mexico Nuclear Proteins Physiological aspects Proteasome Endopeptidase Complex - genetics Proteins Proteolysis Proto-Oncogene Proteins c-bcl-2 Single nucleotide polymorphisms Tetracycline Tetracyclines United States New Mexico Massachusetts Inflammation NF-kappaB Peptides Apoptosis
ISSN:	1558-8238, 0021-9738, 1558-8238
On-line přístup:	Získat plný text
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