Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with r...

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Veröffentlicht in:	The lancet respiratory medicine Jg. 4; H. 1; S. 49
Hauptverfasser:	Pankhurst, Louise J, Del Ojo Elias, Carlos, Votintseva, Antonina A, Walker, Timothy M, Cole, Kevin, Davies, Jim, Fermont, Jilles M, Gascoyne-Binzi, Deborah M, Kohl, Thomas A, Kong, Clare, Lemaitre, Nadine, Niemann, Stefan, Paul, John, Rogers, Thomas R, Roycroft, Emma, Smith, E Grace, Supply, Philip, Tang, Patrick, Wilcox, Mark H, Wordsworth, Sarah, Wyllie, David, Xu, Li, Crook, Derrick W
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.01.2016
Schlagworte:	Antitubercular Agents Canada Cohort Studies Drug Resistance, Multiple, Bacterial - genetics Early Medical Intervention France Germany Humans Ireland Microbial Sensitivity Tests Mycobacterium tuberculosis - genetics Polymorphism, Single Nucleotide Prospective Studies Sequence Analysis, DNA - economics Sequence Analysis, DNA - methods Time Factors Tuberculosis - diagnosis Tuberculosis, Multidrug-Resistant - diagnosis United Kingdom
ISSN:	2213-2619, 2213-2619
Online-Zugang:	Weitere Angaben
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