Cerebral lateralization of praxis in right- and left-handedness: Same pattern, different strength

We aimed to investigate the effect of hand effector and handedness on the cerebral lateralization of pantomiming learned movements. Fourteen right‐handed and 14 left‐handed volunteers performed unimanual and bimanual tool‐use pantomimes with their dominant or nondominant hand during fMRI. A left hem...

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Bibliographic Details
Published in:Human brain mapping Vol. 33; no. 4; pp. 763 - 777
Main Authors: Vingerhoets, Guy, Acke, Frederic, Alderweireldt, Ann-Sofie, Nys, Jo, Vandemaele, Pieter, Achten, Eric
Format: Journal Article
Language:English
Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.04.2012
Wiley-Liss
John Wiley & Sons, Inc
Subjects:
Adult
bimanual gestures
Biological and medical sciences
Brain Mapping
Cerebral Cortex - physiology
cerebral lateralization
Cognition. Intelligence
Female
functional asymmetry
Functional Laterality - physiology
Fundamental and applied biological sciences. Psychology
Gestures
handedness
hemispheric specialization
Humans
Image Interpretation, Computer-Assisted
Investigative techniques, diagnostic techniques (general aspects)
lateralization
Magnetic Resonance Imaging
Male
Medical sciences
Mental imagery. Mental representation
Movement - physiology
Nervous system
pantomiming
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Radiodiagnosis. Nmr imagery. Nmr spectrometry
tool use
transitive gestures
unimanual gestures
Young Adult
Nervous system diseases
Hemispheric specialization
Radiodiagnosis
Central nervous system
pantomiming
Encephalon
Manual task
Handedness
lateralization
unimanual gestures
Asymmetry
cerebral lateralization
transitive gestures
tool use
functional asymmetry
bimanual gestures
Strength
ISSN:1065-9471, 1097-0193, 1097-0193
Online Access:Get full text
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Summary:We aimed to investigate the effect of hand effector and handedness on the cerebral lateralization of pantomiming learned movements. Fourteen right‐handed and 14 left‐handed volunteers performed unimanual and bimanual tool‐use pantomimes with their dominant or nondominant hand during fMRI. A left hemispheric lateralization was observed in the right‐ and left‐handed group regardless of which hand(s) performed the task. Asymmetry was most marked in the dorsolateral prefrontal cortex (DLPFC), premotor cortex (PMC), and superior and inferior parietal lobules (SPL and IPL). Unimanual pantomimes did not reveal any significant differences in asymmetric cerebral activation patterns between left‐ and right‐handers. Bimanual pantomimes showed increased left premotor and posterior parietal activation in left‐ and right‐handers. Lateralization indices (LI) of the 10% most active voxels in DLPFC, PMC, SPL, and IPL were calculated for each individual in a contrast that compared all tool versus all control conditions. Left‐handers showed a significantly reduced overall LI compared with right‐handers. This was mainly due to diminished asymmetry in the IPL and SPL. We conclude that the recollection and pantomiming of learned gestures recruits a similar left lateralized activation pattern in right and left‐handed individuals. Handedness only influences the strength (not the side) of the lateralization, with left‐handers showing a reduced degree of asymmetry that is most readily observed over the posterior parietal region. Together with similar findings in language and visual processing, these results point to a lesser hemispheric specialization in left‐handers that may be considered in the cost/benefit assessment to explain the disproportionate handedness polymorphism in humans. Hum Brain Mapp, 2012. © 2011 Wiley Periodicals, Inc.
Bibliography:Fund for Scientific Research, Flanders - No. G.0555.11
ArticleID:HBM21247
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ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 14
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ISSN:1065-9471
1097-0193
1097-0193
DOI:10.1002/hbm.21247