A Sensitive Method for Determination 1,25-Dihydroxyvitamin D3 in Human Brain using Ultra-Pressure Liquid Chromatography Tandem Mass Spectrometry

The hormonally active form of vitamin D, 1,25-Dihydroxyvitamin D3 [1,25(OH)2D3], has been associated with neuroprotective effects in the brain, but has been difficult to measure in human brain tissue because of its low concentration. The aim of this study was to develop and validate a sensitive meth...

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Bibliographic Details
Published in:	Current developments in nutrition Vol. 8; no. 8; p. 104418
Main Authors:	Xuan, Andrew, Dolnikowski, Gregory G, Booth, Sarah L, Shea, M Kyla, Schneider, Julie A, Fu, Xueyan
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.08.2024 Oxford University Press American Society for Nutrition Elsevier
Subjects:	1,25-dihydroxyvitamin D3 brain Brief Communication: Research Report Degeneration Health aspects Liquid chromatography Mass spectrometry Measurement Nervous system neurodegenerative diseases QTRAP Vitamin D Vitamin D3 United States LOD 1,25-dihydroxyvitamin D3 QTRAP PTAD RSD VDR MT 1,25(OH)2D3 SPE IS brain CR neurodegenerative diseases Vitamin D 25(OH)D3 AWS
ISSN:	2475-2991, 2475-2991
Online Access:	Get full text
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