Gut-derived short-chain fatty acids modulate skin barrier integrity by promoting keratinocyte metabolism and differentiation

Barrier integrity is central to the maintenance of healthy immunological homeostasis. Impaired skin barrier function is linked with enhanced allergen sensitization and the development of diseases such as atopic dermatitis (AD), which can precede the development of other allergic disorders, for examp...

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Veröffentlicht in:	Mucosal immunology Jg. 15; H. 5; S. 908 - 926
Hauptverfasser:	Trompette, Aurélien, Pernot, Julie, Perdijk, Olaf, Alqahtani, Rayed Ali A, Domingo, Jaime Santo, Camacho-Muñoz, Dolores, Wong, Nicholas C, Kendall, Alexandra C, Wiederkehr, Andreas, Nicod, Laurent P, Nicolaou, Anna, von Garnier, Christophe, Ubags, Niki D J, Marsland, Benjamin J
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Limited 01.08.2022
Schlagworte:	Allergens Asthma Atopic dermatitis Child Dermatitis Dermatitis, Atopic Diet Dietary Fiber Disease Eczema Epidemiology Fatty acids Fatty Acids, Volatile Food allergies Food Hypersensitivity Gene expression Homeostasis Humans Hypotheses Immunology Inflammation Keratinocytes Lifestyles Lipids Metabolism Metabolites Mitochondria Skin Skin diseases Westernization
ISSN:	1933-0219, 1935-3456, 1935-3456
Online-Zugang:	Volltext
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