Direct cell reprogramming: approaches, mechanisms and progress

The reprogramming of somatic cells with defined factors, which converts cells from one lineage into cells of another, has greatly reshaped our traditional views on cell identity and cell fate determination. Direct reprogramming (also known as transdifferentiation) refers to cell fate conversion with...

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Vydáno v:	Nature reviews. Molecular cell biology Ročník 22; číslo 6; s. 410 - 424
Hlavní autoři:	Wang, Haofei, Yang, Yuchen, Liu, Jiandong, Qian, Li
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Nature Publishing Group 01.06.2021
Témata:	Animals Cardiomyocytes Cell Differentiation - genetics Cell Differentiation - physiology Cell fate Cell Transdifferentiation - genetics Cell Transdifferentiation - physiology Cellular Reprogramming - genetics Cellular Reprogramming - physiology Epigenesis, Genetic - genetics Epigenetics Fibroblasts Humans Maturation Medicine Metabolism Molecular modelling Non-coding RNA Pluripotency Somatic cells Stem cells Therapeutic applications Transcription factors Translation
ISSN:	1471-0072, 1471-0080, 1471-0080
On-line přístup:	Získat plný text
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