Whole-genome sequence analysis of clinically isolated carbapenem resistant Escherichia coli from Iran
Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resis...
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| Vydané v: | BMC microbiology Ročník 23; číslo 1; s. 49 - 10 |
|---|---|
| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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London
BioMed Central
27.02.2023
BioMed Central Ltd Springer Nature B.V BMC |
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| ISSN: | 1471-2180, 1471-2180 |
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| Abstract | Background
The emergence of carbapenem-resistant
Enterobacterales
(CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of
Escherichia coli
and the genomic features of carbapenem resistant isolates were investigated.
Methods
The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of
bla
OXA-48
,
bla
KPC
,
bla
NDM
, and
bla
VIM
carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms.
Results
Four isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant
E. coli
(CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (
n =
2), ST361 (
n =
1) and ST648 (
n =
1). NDM was detected in all CREC isolates (NDM-1 (
n =
1) and NMD-5 (
n =
3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected
bla
CTX-M-15
,
bla
CMY-145
,
bla
CMY-42
and
bla
TEM-1
(with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was
mcr
-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins.
Conclusion
About 1.9% of
E. coli
isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. |
|---|---|
| AbstractList | The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated. The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of bla.sub.OXA-48, bla.sub.KPC, bla.sub.NDM, and bla.sub.VIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms. Four isolates (3.8%) revealed imipenem MIC of [greater than or equal to]32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected bla.sub.CTX-M-15, bla.sub.CMY-145, bla.sub.CMY-42 and bla.sub.TEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins. About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated.BACKGROUNDThe emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated.The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of blaOXA-48, blaKPC, blaNDM, and blaVIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms.METHODSThe susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of blaOXA-48, blaKPC, blaNDM, and blaVIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms.Four isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected blaCTX-M-15, blaCMY-145, blaCMY-42 and blaTEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins.RESULTSFour isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected blaCTX-M-15, blaCMY-145, blaCMY-42 and blaTEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins.About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future.CONCLUSIONAbout 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. BackgroundThe emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated.MethodsThe susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of blaOXA-48, blaKPC, blaNDM, and blaVIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms.ResultsFour isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected blaCTX-M-15, blaCMY-145, blaCMY-42 and blaTEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins.ConclusionAbout 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. Abstract Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated. Methods The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of bla OXA-48, bla KPC, bla NDM, and bla VIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms. Results Four isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected bla CTX-M-15, bla CMY-145, bla CMY-42 and bla TEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins. Conclusion About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated. Methods The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of bla OXA-48 , bla KPC , bla NDM , and bla VIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms. Results Four isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 ( n = 2), ST361 ( n = 1) and ST648 ( n = 1). NDM was detected in all CREC isolates (NDM-1 ( n = 1) and NMD-5 ( n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected bla CTX-M-15 , bla CMY-145 , bla CMY-42 and bla TEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr -negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins. Conclusion About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated. The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of bla , bla , bla , and bla carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms. Four isolates (3.8%) revealed imipenem MIC of ≥32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected bla , bla , bla and bla (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins. About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clinical isolates of Escherichia coli and the genomic features of carbapenem resistant isolates were investigated. Methods The susceptibility to imipenem, tigecycline and colistin was tested by broth dilution method. Susceptibility to other classes of antimicrobials was examined by disk diffusion test. The presence of bla.sub.OXA-48, bla.sub.KPC, bla.sub.NDM, and bla.sub.VIM carbapenemase genes was examined by PCR. Molecular characteristics of carbapenem resistant isolates were further investigated by whole-genome sequencing (WGS) using Illumina and Nanopore platforms. Results Four isolates (3.8%) revealed imipenem MIC of [greater than or equal to]32 mg/L and positive results for modified carbapenem inactivation method and categorized as carbapenem resistant E. coli (CREC). Colistin, nitrofurantoin, fosfomycin, and tigecycline were the most active agents against all isolates (total susceptibility rate of 99, 99, 96 and 95.2% respectively) with the last three compounds being found as the most active antimicrobials for carbapenem resistant isolates (susceptibility rate of 100%). According to Multilocus Sequence Type (MLST) analysis the 4 CREC isolates belonged to ST167 (n = 2), ST361 (n = 1) and ST648 (n = 1). NDM was detected in all CREC isolates (NDM-1 (n = 1) and NMD-5 (n = 3)) among which one isolate co-harbored NDM-5 and OXA-181 carbapenemases. WGS further detected bla.sub.CTX-M-15, bla.sub.CMY-145, bla.sub.CMY-42 and bla.sub.TEM-1 (with different frequencies) among CREC isolates. Co-occurrence of NDM-type carbapenemase and 16S rRNA methyltransferase RmtB and RmtC was found in two isolates belonging to ST167 and ST648. A colistin-carbapenem resistant isolate which was mcr-negative, revealed various amino acid substitutions in PmrB, PmrD and PhoPQ proteins. Conclusion About 1.9% of E. coli isolates studied here were resistant to imipenem, colistin and/or amikacin which raises the concern about the outbreaks of difficult-to-treat infection by these emerging superbugs in the future. Keywords: Carbapenem resistance, Escherichia coli, NDM-1, NDM-5, Whole genome sequencing, Epidemiology |
| ArticleNumber | 49 |
| Audience | Academic |
| Author | Barmudeh, Samaneh Cirillo, Daniela Maria Kafil, Hossein Samadi Omrani, Maryam Batignani, Virginia Ghodousi, Arash Haeili, Mehri Zeinalzadeh, Narges |
| Author_xml | – sequence: 1 givenname: Mehri surname: Haeili fullname: Haeili, Mehri email: m.haeili@tabrizu.ac.ir, m.haeili@yahoo.com organization: Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz – sequence: 2 givenname: Samaneh surname: Barmudeh fullname: Barmudeh, Samaneh organization: Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz – sequence: 3 givenname: Maryam surname: Omrani fullname: Omrani, Maryam organization: IRCCS San Raffaele Scientific Institute – sequence: 4 givenname: Narges surname: Zeinalzadeh fullname: Zeinalzadeh, Narges organization: Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz – sequence: 5 givenname: Hossein Samadi surname: Kafil fullname: Kafil, Hossein Samadi organization: Drug Applied Research Center, Faculty of Medicine, Tabriz University of Medical Sciences – sequence: 6 givenname: Virginia surname: Batignani fullname: Batignani, Virginia organization: Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute – sequence: 7 givenname: Arash surname: Ghodousi fullname: Ghodousi, Arash email: ghodousi.arash@hsr.it organization: Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University – sequence: 8 givenname: Daniela Maria surname: Cirillo fullname: Cirillo, Daniela Maria organization: Emerging Bacterial Pathogens Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/36850019$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1128_spectrum_02900_24 crossref_primary_10_1186_s12866_024_03525_9 crossref_primary_10_1371_journal_pone_0310026 |
| Cites_doi | 10.1093/cid/ciz824 10.1002/jcla.23041 10.1016/j.diagmicrobio.2010.12.002 10.3109/1040841X.2011.559944 10.1128/AAC.00368-16 10.5812/archcid.62029 10.1016/j.idc.2016.02.011 10.3389/fmicb.2019.00080 10.1089/mdr.2019.0290 10.1128/AAC.01009-09 10.1186/s12866-021-02307-x 10.1016/j.ijantimicag.2018.03.016 10.1128/CMR.00115-18 10.1093/bioinformatics/btu153 10.1038/s41429-020-0350-1 10.1186/s13059-020-02244-4 10.1093/bioinformatics/btv383 10.1128/AAC.00859-16 10.1038/nrmicro818 10.3389/fmicb.2021.702006 10.3390/microorganisms10030615 10.1111/1469-0691.12697 10.1128/AAC.02379-15 10.1099/jmm.0.001513 10.1080/14787210.2018.1425139 10.1128/mSphere.00269-20 10.3389/fmicb.2022.818548 10.1093/jac/dku482 10.1128/AAC.02183-19 10.3389/fcimb.2021.654852 10.3389/fmicb.2017.02470 10.1186/s13099-019-0282-0 10.1016/j.meegid.2017.10.003 10.3389/fmicb.2019.02957 10.1016/j.jgar.2022.07.023 10.1038/s41598-020-61158-0 10.1186/s12866-017-1012-8 10.1371/journal.pcbi.1005595 10.1093/bioinformatics/btu170 10.1073/pnas.1616248114 |
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| DOI | 10.1186/s12866-023-02796-y |
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| References | Y Doi (2796_CR28) 2016; 30 AM Bolger (2796_CR36) 2014; 30 TM Gruber (2796_CR13) 2015; 70 2796_CR10 J Manyahi (2796_CR16) 2022; 71 2796_CR31 2796_CR34 M Haeili (2796_CR37) 2022; 31 T Seemann (2796_CR42) 2014; 30 K Bush (2796_CR6) 2010; 54 J Huang (2796_CR26) 2020; 26 AM Wailan (2796_CR12) 2016; 60 D Aguilera-Alonso (2796_CR14) 2020; 64 KM Kazmierczak (2796_CR7) 2016; 60 GC Cerqueira (2796_CR3) 2017; 114 W-H Zhao (2796_CR8) 2011; 37 P Nordmann (2796_CR5) 2019; 69 G Holley (2796_CR39) 2021; 22 JB Kaper (2796_CR9) 2004; 2 E Taylor (2796_CR29) 2018; 52 2796_CR1 NG El Chakhtoura (2796_CR4) 2018; 16 C Fournier (2796_CR30) 2022; 10 L Poirel (2796_CR35) 2011; 70 B Berbers (2796_CR38) 2020; 10 S Han (2796_CR27) 2020; 73 2796_CR21 W Wu (2796_CR22) 2019; 32 A Garcia-Fernandez (2796_CR18) 2020; 5 2796_CR24 F Li (2796_CR15) 2021; 21 GW Procop (2796_CR32) 2020 Y Huang (2796_CR17) 2016; 60 Y Park (2796_CR19) 2020; 34 F Li (2796_CR25) 2022; 13 Y-F Zhou (2796_CR23) 2020; 10 L Tzouvelekis (2796_CR2) 2014; 20 AU Khan (2796_CR20) 2017; 17 RR Wick (2796_CR41) 2015; 31 RR Wick (2796_CR40) 2017; 13 H Solgi (2796_CR11) 2017; 55 MP Weinstein (2796_CR33) 2021 |
| References_xml | – volume: 69 start-page: S521 issue: Supplement_7 year: 2019 ident: 2796_CR5 publication-title: Clin Infect Dis doi: 10.1093/cid/ciz824 – volume: 34 start-page: e23041 issue: 2 year: 2020 ident: 2796_CR19 publication-title: J Clin Lab Anal doi: 10.1002/jcla.23041 – volume: 70 start-page: 119 issue: 1 year: 2011 ident: 2796_CR35 publication-title: Diagn Microbiol Infect Dis doi: 10.1016/j.diagmicrobio.2010.12.002 – volume: 37 start-page: 214 issue: 3 year: 2011 ident: 2796_CR8 publication-title: Crit Rev Microbiol doi: 10.3109/1040841X.2011.559944 – volume: 60 start-page: 4082 issue: 7 year: 2016 ident: 2796_CR12 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.00368-16 – ident: 2796_CR10 doi: 10.5812/archcid.62029 – volume: 30 start-page: 523 issue: 2 year: 2016 ident: 2796_CR28 publication-title: Infect Dis Clin doi: 10.1016/j.idc.2016.02.011 – ident: 2796_CR1 doi: 10.3389/fmicb.2019.00080 – volume: 26 start-page: 1442 issue: 12 year: 2020 ident: 2796_CR26 publication-title: Microb Drug Resist doi: 10.1089/mdr.2019.0290 – volume: 54 start-page: 969 issue: 3 year: 2010 ident: 2796_CR6 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.01009-09 – volume: 21 start-page: 1 issue: 1 year: 2021 ident: 2796_CR15 publication-title: BMC Microbiol doi: 10.1186/s12866-021-02307-x – volume: 52 start-page: 278 issue: 2 year: 2018 ident: 2796_CR29 publication-title: Int J Antimicrob Agents doi: 10.1016/j.ijantimicag.2018.03.016 – volume: 32 start-page: e00115 issue: 2 year: 2019 ident: 2796_CR22 publication-title: Clin Microbiol Rev doi: 10.1128/CMR.00115-18 – volume: 30 start-page: 2068 issue: 14 year: 2014 ident: 2796_CR42 publication-title: Bioinform doi: 10.1093/bioinformatics/btu153 – volume: 73 start-page: 852 issue: 12 year: 2020 ident: 2796_CR27 publication-title: J Antibio doi: 10.1038/s41429-020-0350-1 – volume-title: Koneman's color atlas and textbook of diagnostic microbiology year: 2020 ident: 2796_CR32 – volume: 22 start-page: 1 issue: 1 year: 2021 ident: 2796_CR39 publication-title: Genome Biol doi: 10.1186/s13059-020-02244-4 – volume: 31 start-page: 3350 issue: 20 year: 2015 ident: 2796_CR41 publication-title: Bioinform. doi: 10.1093/bioinformatics/btv383 – volume: 60 start-page: 4364 issue: 7 year: 2016 ident: 2796_CR17 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.00859-16 – volume: 2 start-page: 123 issue: 2 year: 2004 ident: 2796_CR9 publication-title: Nat Rev Microbiol doi: 10.1038/nrmicro818 – ident: 2796_CR21 doi: 10.3389/fmicb.2021.702006 – volume: 10 start-page: 615 issue: 3 year: 2022 ident: 2796_CR30 publication-title: Microorgan doi: 10.3390/microorganisms10030615 – volume: 20 start-page: 862 issue: 9 year: 2014 ident: 2796_CR2 publication-title: Clin Microbiol Infect doi: 10.1111/1469-0691.12697 – volume: 60 start-page: 1067 issue: 2 year: 2016 ident: 2796_CR7 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.02379-15 – volume: 71 start-page: 001513 issue: 2 year: 2022 ident: 2796_CR16 publication-title: J Med Microbiol doi: 10.1099/jmm.0.001513 – volume: 16 start-page: 89 issue: 2 year: 2018 ident: 2796_CR4 publication-title: Expert Rev Anti-Infect Ther doi: 10.1080/14787210.2018.1425139 – volume: 5 start-page: e00269 issue: 2 year: 2020 ident: 2796_CR18 publication-title: MSphere. doi: 10.1128/mSphere.00269-20 – volume: 13 start-page: 818548 year: 2022 ident: 2796_CR25 publication-title: Front Microbiol doi: 10.3389/fmicb.2022.818548 – volume: 70 start-page: 1026 issue: 4 year: 2015 ident: 2796_CR13 publication-title: J Antimicrob Chemother doi: 10.1093/jac/dku482 – volume: 64 start-page: e02183 issue: 3 year: 2020 ident: 2796_CR14 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.02183-19 – ident: 2796_CR31 doi: 10.3389/fcimb.2021.654852 – ident: 2796_CR24 doi: 10.3389/fmicb.2017.02470 – ident: 2796_CR34 doi: 10.1186/s13099-019-0282-0 – volume: 55 start-page: 318 year: 2017 ident: 2796_CR11 publication-title: 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| Snippet | Background
The emergence of carbapenem-resistant
Enterobacterales
(CRE) continues to threaten public health due to limited therapeutic options. In the current... The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the... Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current... BackgroundThe emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current... Abstract Background The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the... |
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| SubjectTerms | Amikacin Amino acids Analysis Antibiotics Antimicrobial agents Beta lactamases Biological Microscopy Biomedical and Life Sciences Carbapenem resistance Carbapenem-Resistant Enterobacteriaceae - genetics Carbapenemase Carbapenems - pharmacology Chromosomes Clinical isolates Colistin Colistin - pharmacology Dilution Disease control DNA sequencing Drug resistance Drug resistance in microorganisms E coli Enzymes Epidemiology Escherichia coli Escherichia coli - genetics Escherichia coli infections Escherichia coli Proteins Fosfomycin Gene sequencing Genes Genetic aspects Genomes Genomics Health aspects Identification and classification Imipenem Inactivation Infections Iran Life Sciences Microbiology Multilocus Sequence Typing Mycology NDM-1 NDM-5 Nitrofurantoin Nucleotide sequence Nucleotide sequencing Parasitology Plasmids Proteins Public health Risk factors RNA, Ribosomal, 16S rRNA (adenosine-2'-0'-)-methyltransferase rRNA 16S rRNA methyltransferase Sulbactam Susceptibility Tazobactam Tigecycline Virology Whole genome sequencing |
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| Title | Whole-genome sequence analysis of clinically isolated carbapenem resistant Escherichia coli from Iran |
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