Feasibility of quantifying SDC2 methylation in stool DNA for early detection of colorectal cancer

Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected genes and early during CRC development, which has emerged as a new epigenetic biomarker for early detection of CRC. Previou...

Full description

Saved in:

Bibliographic Details
Published in:	Clinical epigenetics Vol. 9; no. 1; pp. 126 - 11
Main Authors:	Oh, Tae Jeong, Oh, Hyun Il, Seo, Yang Yei, Jeong, Dongjun, Kim, Changjin, Kang, Hyoun Woo, Han, Yoon Dae, Chung, Hyun Cheol, Kim, Nam Kyu, An, Sungwhan
Format:	Journal Article
Language:	English
Published:	London BioMed Central 04.12.2017 BioMed Central Ltd BMC
Subjects:	Adult Aged Analysis Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Cancer epigenetics and diagnostics Cancer screening Colorectal cancer Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics CpG Islands Development and progression DNA Methylation Early detection Epigenesis, Genetic Feasibility Studies Feces - chemistry Female Gene Function HCT116 Cells Health aspects HT29 Cells Human Genetics Humans Male Methylation Middle Aged Mortality Precancerous lesion SDC2 Sensitivity and Specificity Sequence Analysis, DNA Stool DNA Syndecan-2 - genetics Methylation Stool DNA Precancerous lesion Early detection Colorectal cancer SDC2
ISSN:	1868-7075, 1868-7083, 1868-7083
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!