Feasibility of quantifying SDC2 methylation in stool DNA for early detection of colorectal cancer

Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected genes and early during CRC development, which has emerged as a new epigenetic biomarker for early detection of CRC. Previou...

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Vydáno v:	Clinical epigenetics Ročník 9; číslo 1; s. 126 - 11
Hlavní autoři:	Oh, Tae Jeong, Oh, Hyun Il, Seo, Yang Yei, Jeong, Dongjun, Kim, Changjin, Kang, Hyoun Woo, Han, Yoon Dae, Chung, Hyun Cheol, Kim, Nam Kyu, An, Sungwhan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 04.12.2017 BioMed Central Ltd BMC
Témata:	Adult Aged Analysis Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Cancer epigenetics and diagnostics Cancer screening Colorectal cancer Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics CpG Islands Development and progression DNA Methylation Early detection Epigenesis, Genetic Feasibility Studies Feces - chemistry Female Gene Function HCT116 Cells Health aspects HT29 Cells Human Genetics Humans Male Methylation Middle Aged Mortality Precancerous lesion SDC2 Sensitivity and Specificity Sequence Analysis, DNA Stool DNA Syndecan-2 - genetics Methylation Stool DNA Precancerous lesion Early detection Colorectal cancer SDC2
ISSN:	1868-7075, 1868-7083, 1868-7083
On-line přístup:	Získat plný text
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