Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?

Background Type 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral insulin resistance on AD aetiopathogenesis in non-diabetic patients is still debated. Here we evaluated the influence of insulin resistance on brain glucos...

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Bibliographic Details
Published in:	Alzheimer's research & therapy Vol. 13; no. 1; pp. 47 - 11
Main Authors:	Femminella, Grazia Daniela, Livingston, Nicholas R., Raza, Sanara, van der Doef, Thalia, Frangou, Eleni, Love, Sharon, Busza, Gail, Calsolaro, Valeria, Carver, Stefan, Holmes, Clive, Ritchie, Craig W., Lawrence, Robert M., McFarlane, Brady, Tadros, George, Ridha, Basil H., Bannister, Carol, Walker, Zuzana, Archer, Hilary, Coulthard, Elizabeth, Underwood, Ben, Prasanna, Aparna, Koranteng, Paul, Karim, Salman, Junaid, Kehinde, McGuinness, Bernadette, Passmore, Anthony Peter, Nilforooshan, Ramin, Macharouthu, Ajayverma, Donaldson, Andrew, Thacker, Simon, Russell, Gregor, Malik, Naghma, Mate, Vandana, Knight, Lucy, Kshemendran, Sajeev, Tan, Tricia, Holscher, Christian, Harrison, John, Brooks, David J., Ballard, Clive, Edison, Paul
Format:	Journal Article
Language:	English
Published:	London BioMed Central 17.02.2021 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Activities of daily living Alzheimer's disease Analysis Biomedical and Life Sciences Biomedicine Care and treatment Cognition & reasoning Dementia Development and progression Diabetes Geriatric Psychiatry Geriatrics Geriatrics/Gerontology Glucose Insulin resistance Magnetic resonance imaging Metabolism Neurodegeneration Neurology Neurosciences Older people Peptides Plasma Population Positron emission tomography imaging United Kingdom Insulin resistance Alzheimer’s disease Magnetic resonance imaging Positron emission tomography imaging
ISSN:	1758-9193, 1758-9193
Online Access:	Get full text
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