Assembly and transport of filovirus nucleocapsids

Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs) located in the perinuclear region. The formation of these IBs is induced mainly by the accumulation of the filoviral nucleoprotein NP, which recruits the other nucleocapsid proteins, the polymerase co-factor VP3...

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Bibliographic Details
Published in:	PLoS pathogens Vol. 18; no. 7; p. e1010616
Main Authors:	Dolnik, Olga, Becker, Stephan
Format:	Journal Article
Language:	English
Published:	San Francisco Public Library of Science 28.07.2022 Public Library of Science (PLoS)
Subjects:	Actin Amino acids Assembly Binding sites Biological transport Biology and Life Sciences Budding C-Terminus Filoviridae Genetic aspects Genomes Genomics Handedness Helices Inclusion bodies Medicine and Health Sciences N-Terminus Nucleocapsids Nucleoproteins Physiological aspects Plasma Polymerization Protein interaction Protein-protein interactions Proteins Review Ribonucleic acid RNA RNA viruses Structure Synthesis Tomography Transcription factors Transmission electron microscopy Viral proteins Virus research VP24 protein Germany
ISSN:	1553-7374, 1553-7366, 1553-7374
Online Access:	Get full text
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