Limited evidence for blood eQTLs in human sexual dimorphism

Background The genetic underpinning of sexual dimorphism is very poorly understood. The prevalence of many diseases differs between men and women, which could be in part caused by sex-specific genetic effects. Nevertheless, only a few published genome-wide association studies (GWAS) were performed s...

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Vydáno v:	Genome medicine Ročník 14; číslo 1; s. 89 - 13
Hlavní autoři:	Porcu, Eleonora, Claringbould, Annique, Weihs, Antoine, Lepik, Kaido, Richardson, Tom G., Völker, Uwe, Santoni, Federico A., Teumer, Alexander, Franke, Lude, Reymond, Alexandre, Kutalik, Zoltán
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 11.08.2022 BioMed Central Ltd Springer Nature B.V BMC
Témata:	Amyotrophic lateral sclerosis Analysis Biobanks Bioinformatics Biomedical and Life Sciences Biomedicine Blood Cancer Research Cohort analysis Consortia Diabetes Female Gender differences Gene expression Gene loci Genes Genome-wide association studies Genome-Wide Association Study - methods Genomes Genomics Human Genetics Humans Male Medicine/Public Health Metabolomics Polymorphism, Single Nucleotide Population Quantitative genetics Quantitative Trait Loci Sex Characteristics Sexes Sexual dimorphism Single nucleotide polymorphisms Single-nucleotide polymorphism Systems Biology Testosterone Transcriptome Transcriptomes Type 2 diabetes Womens health Netherlands
ISSN:	1756-994X, 1756-994X
On-line přístup:	Získat plný text
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