The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS)

Background Much progress has been made in mapping genetic abnormalities linked to amyotrophic lateral sclerosis (ALS), but the majority of cases still present with no known underlying cause. Furthermore, even in families with a shared genetic abnormality there is significant phenotypic variability,...

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Vydané v:	BMC medicine Ročník 19; číslo 1; s. 13 - 14
Hlavní autori:	Boddy, Sarah L., Giovannelli, Ilaria, Sassani, Matilde, Cooper-Knock, Johnathan, Snyder, Michael P., Segal, Eran, Elinav, Eran, Barker, Lynne A., Shaw, Pamela J., McDermott, Christopher J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 20.01.2021 BioMed Central Ltd Springer Nature B.V BMC
Predmet:	Abnormalities ALS Amyotrophic lateral sclerosis Animal diseases Animal models Antibiotics Bioavailability Biodiversity Biomedicine Causes of Development and progression Digestive system Disease Disease modifiers Gastrointestinal tract Gene mapping Genetic abnormalities Genetic variability Genetics Gut microbiota Health aspects Host-bacteria relationships Intestinal microflora Intestine Medicine Medicine & Public Health Metabolites Microbial Microbial activity Microbial metabolites Microbiome Microbiomes Microbiota Microbiota (Symbiotic organisms) Microorganisms Mutation Neurodegeneration Neuroprotection Neurotoxicity Neurotransmitters Nutrients Pathogenesis Precision medicine Review Sample variance Therapeutic targets United States ALS Disease modifiers Amyotrophic lateral sclerosis Microbial Microbial metabolites Microbiome
ISSN:	1741-7015, 1741-7015
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