Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death

Eukaryotic cells fold and assemble membrane and secreted proteins in the endoplasmic reticulum (ER), before delivery to other cellular compartments or the extracellular environment. Correctly folded proteins are released from the ER, and poorly folded proteins are retained until they achieve stable...

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Veröffentlicht in:	The American journal of pathology Jg. 185; H. 7; S. 1800
Hauptverfasser:	Hiramatsu, Nobuhiko, Chiang, Wei-Chieh, Kurt, Timothy D, Sigurdson, Christina J, Lin, Jonathan H
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2015
Schlagworte:	Animals Apoptosis Awards and Prizes eIF-2 Kinase - metabolism Endoplasmic Reticulum - metabolism Endoplasmic Reticulum Stress Endoribonucleases - metabolism Eukaryotic Cells - physiology Humans Mammals Models, Biological Molecular Chaperones - metabolism Pathology Protein Biosynthesis Protein Serine-Threonine Kinases - metabolism Signal Transduction Societies, Medical Unfolded Protein Response United States United States
ISSN:	1525-2191, 1525-2191
Online-Zugang:	Weitere Angaben
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