Metal nanoparticles: understanding the mechanisms behind antibacterial activity

As the field of nanomedicine emerges, there is a lag in research surrounding the topic of nanoparticle (NP) toxicity, particularly concerned with mechanisms of action. The continuous emergence of bacterial resistance has challenged the research community to develop novel antibiotic agents. Metal NPs...

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Bibliographic Details
Published in:	Journal of nanobiotechnology Vol. 15; no. 1; pp. 65 - 20
Main Authors:	Slavin, Yael N., Asnis, Jason, Häfeli, Urs O., Bach, Horacio
Format:	Journal Article
Language:	English
Published:	London BioMed Central 03.10.2017 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Animals Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Antibacterial agents Antibiotics Antimicrobial agents Bacteria Bacteria - cytology Bacteria - drug effects Bacteria - genetics Bacteria - metabolism Bacterial Infections - drug therapy Bacterial Infections - microbiology Bacterial Proteins - genetics Bacterial Proteins - metabolism Biochemistry Biotechnology Chemistry Chemistry and Materials Science Damage Dosage and administration Drug resistance in microorganisms E coli Escherichia coli Gene expression Gene Expression Regulation, Bacterial - drug effects Gene regulation Gram-negative bacteria Gram-positive bacteria Health aspects Humans Mechanism of defense Metal Nanoparticles - chemistry Metals Molecular Medicine Nanoparticles Nanotechnology Proteins Proteomics Reactive oxygen species Reactive Oxygen Species - metabolism Review ROS Staphylococcus aureus Studies Toxicity Transcriptome - drug effects Transcriptomics Transmission electron microscopy Nanoparticles Transcriptomics Metals Gene regulation ROS Proteomics Bacteria Mechanism of defense Antibacterial resistance
ISSN:	1477-3155, 1477-3155
Online Access:	Get full text
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