Pharmacokinetics of rectal levetiracetam as add-on treatment in dogs affected by cluster seizures or status epilepticus

Background Levetiracetam can be used for seizure control alone or in combination with other antiepileptic medications. A previous study achieved the minimum targeted serum drug concentration after rectal administration of levetiracetam in healthy dogs. The purpose of the present study was to determi...

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Bibliographic Details
Published in:	BMC veterinary research Vol. 14; no. 1; p. 189
Main Authors:	Cagnotti, Giulia, Odore, Rosangela, Gardini, Giulia, Amedeo, Stefano, Bertone, Iride, Guerriero, Giulia, Lentini, Laura, Dappiano, Elena, D’Angelo, Antonio
Format:	Journal Article
Language:	English
Published:	London BioMed Central 18.06.2018 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Administration, Rectal Animals anticonvulsants Anticonvulsants - administration & dosage Anticonvulsants - pharmacokinetics Anticonvulsants - therapeutic use Antiepileptic agents Binding sites blood serum Catheters Chromatography Consciousness Dog Diseases - drug therapy Dogs Dosage and administration Drug dosages Drug therapy Emergency Epilepsy Etiracetam Female Health aspects Levetiracetam Male Medicine Medicine & Public Health Neurology Neurology and neuroscience Patients Pharmacokinetics Pilot Projects Piracetam - administration & dosage Piracetam - analogs & derivatives Piracetam - pharmacokinetics Piracetam - therapeutic use protocols Publishing Rectum Research Article Risk factors Seizures Seizures - drug therapy Seizures - veterinary Status Epilepticus - drug therapy Status Epilepticus - veterinary Transgenics Veterinary medicine Veterinary Medicine/Veterinary Science Zoology United States > US Neurology Emergency Pharmacokinetics Epilepsy
ISSN:	1746-6148, 1746-6148
Online Access:	Get full text
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