Diverse reprogramming codes for neuronal identity

The transcriptional programs that establish neuronal identity evolved to produce the rich diversity of neuronal cell types that arise sequentially during development. Remarkably, transient expression of certain transcription factors can also endow non-neural cells with neuronal properties. The relat...

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Bibliographic Details
Published in:	Nature (London) Vol. 557; no. 7705; pp. 375 - 380
Main Authors:	Tsunemoto, Rachel, Lee, Sohyon, Szűcs, Attila, Chubukov, Pavel, Sokolova, Irina, Blanchard, Joel W., Eade, Kevin T., Bruggemann, Jacob, Wu, Chunlei, Torkamani, Ali, Sanna, Pietro Paolo, Baldwin, Kristin K.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.05.2018 Nature Publishing Group
Subjects:	13/100 13/106 13/31 14/63 38/39 45/91 631/378/2571/2578 631/532/2128 9/74 Animals Bioinformatics Cell division Cellular Reprogramming - genetics Cloning DNA binding proteins Fibroblasts Fibroblasts - cytology Fibroblasts - metabolism Gene expression Gene Expression Profiling Gene Regulatory Networks Genes Genomes Humanities and Social Sciences Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Mice multidisciplinary Neural circuitry Neurons Neurons - cytology Neurons - drug effects Neurons - metabolism Neurophysiology Pharmacology Physiological aspects Science Science (multidisciplinary) Sequence Analysis, RNA Single-Cell Analysis Transcription (Genetics) Transcription factors Transcription Factors - metabolism Transcriptome - genetics
ISSN:	0028-0836, 1476-4687, 1476-4687
Online Access:	Get full text
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