Mechanisms of cancer resistance in long-lived mammals

Cancer researchers have traditionally used the mouse and the rat as staple model organisms. These animals are very short-lived, reproduce rapidly and are highly prone to cancer. They have been very useful for modelling some human cancer types and testing experimental treatments; however, these cance...

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Bibliographic Details
Published in:	Nature reviews. Cancer Vol. 18; no. 7; pp. 433 - 441
Main Authors:	Seluanov, Andrei, Gladyshev, Vadim N, Vijg, Jan, Gorbunova, Vera
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.07.2018
Subjects:	Animals Body Size Cancer Cattle Chiroptera Disease Resistance - genetics Disease Resistance - physiology Elephants Horses Humans Longevity Mammals Mice Mole Rats Molecular modelling Mutation Mutation Rate Neoplasms - genetics Neoplasms - metabolism Rats Sciuridae Species Whales
ISSN:	1474-175X, 1474-1768, 1474-1768
Online Access:	Get full text
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