Beyond microRNA – Novel RNAs derived from small non-coding RNA and their implication in cancer

► SnoRNAs and tRNAs are specifically processed to different, functional types of smaller RNAs referred to as sdRNAs and tRFs. ► The expression of many snoRNAs, tRNAs, and derived from them smaller RNAs is altered in human disease and cancer. ► SdRNAs and tRFs share components of the molecular pathwa...

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Vydané v:	Cancer letters Ročník 340; číslo 2; s. 201 - 211
Hlavní autori:	Martens-Uzunova, Elena S., Olvedy, Michael, Jenster, Guido
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Ireland Elsevier Ireland Ltd 01.11.2013 Elsevier Limited
Predmet:	Animals Apoptosis Biomarkers, Tumor Biomarkers, Tumor - genetics Cancer Cell growth Deoxyribonucleic acid diagnosis DNA DNA methylation Evolution, Molecular Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic Predisposition to Disease Genetic Testing genetics Genome, Human Genomes Genomics Genomics - methods Hematology, Oncology and Palliative Medicine High-Throughput Nucleotide Sequencing Humans metabolism methods microRNA MicroRNAs MicroRNAs - metabolism Mitochondrial DNA Neoplasms Neoplasms - diagnosis Neoplasms - genetics Neoplasms - therapy Next generation sequencing Non-coding RNA Oligonucleotide Array Sequence Analysis Phenotype Predictive Value of Tests Prognosis Proteins RNA polymerase RNA, Neoplasm RNA, Neoplasm - metabolism RNA, Small Nucleolar RNA, Small Nucleolar - metabolism RNA, Small Untranslated RNA, Small Untranslated - metabolism RNA, Transfer RNA, Transfer - metabolism Sequence Analysis, RNA snoRNA-derived RNA (sdRNA) Technological change Telomerase therapy transcriptome Transfer RNA tRNA fragment (tRF) snoRNA-derived RNA (sdRNA) microRNA Next generation sequencing Non-coding RNA tRNA fragment (tRF) Cancer
ISSN:	0304-3835, 1872-7980, 1872-7980
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