Lactate in the tumour microenvironment: From immune modulation to therapy

Disordered metabolic states, which are characterised by hypoxia and elevated levels of metabolites, particularly lactate, contribute to the immunosuppression in the tumour microenvironment (TME). Excessive lactate secreted by metabolism-reprogrammed cancer cells regulates immune responses via causin...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	EBioMedicine Ročník 73; s. 103627
Hlavní autoři:	Wang, Zi-Hao, Peng, Wen-Bei, Zhang, Pei, Yang, Xiang-Ping, Zhou, Qiong
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier B.V 01.11.2021 Elsevier
Témata:	Advanced Basic Science Animals Biological Transport Biomarkers Cancer immunity Cancer metabolism Disease Management Disease Susceptibility Energy Metabolism Glycolysis Glycolytic enzymes Humans Immunomodulation Immunotherapy Internal Medicine Lactate Lactic Acid - metabolism Metabolic Networks and Pathways Monocarboxylate transporters Neoplasms - etiology Neoplasms - metabolism Neoplasms - pathology Neoplasms - therapy Review Tumor Microenvironment - immunology Tumour microenvironment Lactate Monocarboxylate transporters Cancer metabolism Cancer immunity Glycolytic enzymes Tumour microenvironment
ISSN:	2352-3964, 2352-3964
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!