Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

Osteoarthritis (OA) is the most common joint disease and is the leading cause of chronic disability among older people. Chondrocyte death and extracellular matrix (ECM) degradation was involved in OA pathogenesis. Ferroptosis was an iron-dependent cell death associated with peroxidation of lipids. H...

Full description

Saved in:

Bibliographic Details
Published in:	EBioMedicine Vol. 76; p. 103847
Main Authors:	Miao, Yu, Chen, Yiwei, Xue, Feng, Liu, Kexin, Zhu, Bin, Gao, Junjie, Yin, Junhui, Zhang, Changqing, Li, Guangyi
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.02.2022 Elsevier
Subjects:	Advanced Basic Science Aged Cell Death China Chondrocyte Extracellular matrix Ferroptosis Ferroptosis - genetics GPX4 Humans Internal Medicine Osteoarthritis Osteoarthritis - genetics Phospholipid Hydroperoxide Glutathione Peroxidase - genetics China Ferroptosis Extracellular matrix Chondrocyte GPX4 Osteoarthritis
ISSN:	2352-3964, 2352-3964
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!