An Update on the Pathogenesis of COVID-19 and the Reportedly Rare Thrombotic Events Following Vaccination

Today the coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a global health problem. After more than a year with the pandemic, although our knowledge has progressed on COVID-19, there are still many unknowns in virological, pathop...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Clinical and applied thrombosis/hemostasis Ročník 27; s. 10760296211021498
Hlavní autori:	Kantarcioglu, Bulent, Iqbal, Omer, Walenga, Jeanine M., Lewis, Bruce, Lewis, Joseph, Carter, Charles A., Singh, Meharvan, Lievano, Fabio, Tafur, Alfonso, Ramacciotti, Eduardo, Gerotziafas, Grigoris T., Jeske, Walter, Fareed, Jawed
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Los Angeles, CA SAGE Publications 2021 SAGE PUBLICATIONS, INC SAGE Publishing
Predmet:	Ad26COVS1 Anticoagulants Autoantibodies Autoantibodies - biosynthesis BNT162 Vaccine ChAdOx1 nCoV-19 Clinical Trials as Topic Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - physiopathology COVID-19 - prevention & control COVID-19 Vaccines COVID-19 Vaccines - adverse effects COVID-19 Vaccines - genetics COVID-19 Vaccines - immunology Disseminated Intravascular Coagulation Disseminated Intravascular Coagulation - epidemiology Disseminated Intravascular Coagulation - etiology Drug Approval Female Genetic Vectors Glycosaminoglycans Glycosaminoglycans - immunology Humans Immunization Life Sciences Male Models, Cardiovascular mRNA Vaccines Pandemics Pandemics - prevention & control Pathogenesis Platelet Factor 4 Platelet Factor 4 - immunology Review Safety SARS-CoV-2 SARS-CoV-2 - genetics SARS-CoV-2 - immunology SARS-CoV-2 - pathogenicity Severe acute respiratory syndrome coronavirus 2 Sinus Thrombosis, Intracranial Sinus Thrombosis, Intracranial - epidemiology Sinus Thrombosis, Intracranial - etiology Thrombosis Thrombosis - epidemiology Thrombosis - etiology Thrombosis - physiopathology Vaccines, Inactivated Vaccines, Inactivated - adverse effects Vaccines, Inactivated - genetics Vaccines, Inactivated - immunology Vaccines, Synthetic Vaccines, Synthetic - adverse effects Vaccines, Synthetic - genetics Vaccines, Synthetic - immunology COVID-19 safety and efficacy SARS-CoV-2 thrombosis thrombocytopenia heparin induced thrombocytopenia
ISSN:	1076-0296, 1938-2723, 1938-2723
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Popis
Shrnutí:	Today the coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a global health problem. After more than a year with the pandemic, although our knowledge has progressed on COVID-19, there are still many unknowns in virological, pathophysiological and immunological aspects. It is obvious that the most efficient solution to end this pandemic are safe and efficient vaccines. This manuscript summarizes the pathophysiological and thrombotic features of COVID-19 and the safety and efficacy of currently approved COVID-19 vaccines with an aim to clarify the recent concerns of thromboembolic events after COVID-19 vaccination. The influx of newer information is rapid, requiring periodic updates and objective assessment of the data on the pathogenesis of COVID-19 variants and the safety and efficacy of currently available vaccines.
Bibliografia:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	1076-0296 1938-2723 1938-2723
DOI:	10.1177/10760296211021498