Mechanisms of Hepatitis B Virus Persistence

Hepatitis B virus (HBV) chronically infects 250 million people worldwide, resulting in nearly one million deaths annually. Studies in recent years have significantly improved our knowledge on the mechanisms of HBV persistence. HBV uses multiple pathways to harness host innate immunity to enhance its...

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Bibliographic Details
Published in:	Trends in microbiology (Regular ed.) Vol. 26; no. 1; pp. 33 - 42
Main Authors:	Tsai, Kuen-Nan, Kuo, Cheng-Fu, Ou, Jing-Hsiung James
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.01.2018 Elsevier Science Ltd
Subjects:	age and maternal effects Age Factors antigens Child Children chronic hepatitis B Chronic infection Disease transmission Gastrointestinal Microbiome - immunology HBV e antigen Hepatitis Hepatitis B Hepatitis B e Antigens Hepatitis B virus Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B virus - pathogenicity Hepatitis B virus - physiology Hepatitis B, Chronic - therapy Host-Pathogen Interactions - immunology Humans Immune system Immunity Immunity, Innate Infectious Disease Transmission, Vertical Innate immunity interferon immune responses Intestinal microflora intestinal microorganisms Life Cycle Stages Maternal Inheritance - immunology Medical treatment Microbiota Offspring people vertical transmission Viral infections Viral Load Viruses chronic hepatitis B vertical transmission HBV e antigen age and maternal effects interferon immune responses
ISSN:	0966-842X, 1878-4380, 1878-4380
Online Access:	Get full text
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