Emerging roles for neogenin and its ligands in CNS development

It is now well established that the netrin guidance cues and their receptors comprise a major molecular guidance system driving axon pathfinding during nervous system development. One netrin receptor, neogenin, is now emerging as a key regulator of many developmental processes throughout the embryo....

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Bibliographic Details
Published in:	Journal of neurochemistry Vol. 106; no. 4; pp. 1483 - 1492
Main Authors:	De Vries, Melissa, Cooper, Helen M
Format:	Journal Article
Language:	English
Published:	Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.08.2008 Blackwell Publishing Ltd Blackwell
Subjects:	Amino Acid Sequence Animals axon guidance Biochemistry Biological and medical sciences Cell adhesion & migration Cell receptors Cell structures and functions Cellular biology Central Nervous System - cytology Central Nervous System - embryology Central Nervous System - physiology CNS development Development. Senescence. Regeneration. Transplantation Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - physiology Humans Ligands Membrane Proteins - chemistry Membrane Proteins - metabolism Membrane Proteins - physiology Molecular and cellular biology Molecular biology Molecular Sequence Data Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) neogenin netrin Neurology repulsive guidance molecule Signal transduction signaling pathways Vertebrates: nervous system and sense organs netrin Embryo Interaction neogenin Central nervous system Nervous system Activation CNS development repulsive guidance molecule Epithelium Adhesion Guidance Signal transduction signaling pathways Development Differentiation axon guidance Biological receptor
ISSN:	0022-3042, 1471-4159, 1471-4159
Online Access:	Get full text
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