Differential Lipid Profiles of Normal Human Brain Matter and Gliomas by Positive and Negative Mode Desorption Electrospray Ionization – Mass Spectrometry Imaging

Desorption electrospray ionization-mass spectrometry (DESI-MS) imaging was used to analyze unmodified human brain tissue sections from 39 subjects sequentially in the positive and negative ionization modes. Acquisition of both MS polarities allowed more complete analysis of the human brain tumor lip...

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Vydáno v:	PloS one Ročník 11; číslo 9; s. e0163180
Hlavní autoři:	Jarmusch, Alan K., Alfaro, Clint M., Pirro, Valentina, Hattab, Eyas M., Cohen-Gadol, Aaron A., Cooks, R. Graham
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 22.09.2016 Public Library of Science (PLoS)
Témata:	Biology and Life Sciences Brain Brain cancer Brain tumors Chemistry Data integration Desorption Discriminant analysis Electrospraying Glioma Histopathology Human subjects Ionization Ions Lipids Mass spectrometry Mass spectroscopy Medical diagnosis Medicine and Health Sciences Metabolites Multisensor fusion Neuroimaging Neurosciences Parenchyma Phospholipids Physical Sciences Principal components analysis Research and Analysis Methods Scientific imaging Sensitivity Spectroscopy Substantia alba Substantia grisea Surgery Tumors Indiana United States > US Indianapolis Indiana
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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