Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

Circular dichroism (CD) spectroscopy is a widely used technique for the study of protein structure. Numerous algorithms have been developed for the estimation of the secondary structure composition from the CD spectra. These methods often fail to provide acceptable results on α/β-mixed or β-structur...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS Jg. 112; H. 24; S. E3095
Hauptverfasser:	Micsonai, András, Wien, Frank, Kernya, Linda, Lee, Young-Ho, Goto, Yuji, Réfrégiers, Matthieu, Kardos, József
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 16.06.2015
Schlagworte:	Algorithms Amyloid beta-Peptides - chemistry beta 2-Microglobulin - chemistry Biophysical Phenomena Circular Dichroism - methods Circular Dichroism - statistics & numerical data Computer Simulation Humans Models, Molecular Peptide Fragments - chemistry Peptides - chemistry Protein Aggregates Protein Folding Protein Structure, Secondary Proteins - chemistry protein fold amyloid circular dichroism protein aggregation secondary structure determination
ISSN:	1091-6490, 1091-6490
Online-Zugang:	Weitere Angaben
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