Noninvasive in vivo monitoring of tissue-specific global gene expression in humans

Circulating cell-free RNA in the blood provides a potential window into the health, phenotype, and developmental programs of a variety of human organs. We used high-throughput methods of RNA analysis such as microarrays and next-generation sequencing to characterize the global landscape circulating...

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Vydáno v:	Proceedings of the National Academy of Sciences - PNAS Ročník 111; číslo 20; s. 7361
Hlavní autoři:	Koh, Winston, Pan, Wenying, Gawad, Charles, Fan, H Christina, Kerchner, Geoffrey A, Wyss-Coray, Tony, Blumenfeld, Yair J, El-Sayed, Yasser Y, Quake, Stephen R
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 20.05.2014
Témata:	Adult Alzheimer Disease - blood Apoptosis Brain - embryology Brain - metabolism Female Gene Expression Profiling - methods Gene Expression Regulation, Developmental Genomics - methods High-Throughput Nucleotide Sequencing - methods Humans Neurodegenerative Diseases - physiopathology Neurons - metabolism Oligonucleotide Array Sequence Analysis Pregnancy RNA - blood Time Factors Transcriptome cell-free nucleic acids genomics noninvasive diagnostics
ISSN:	1091-6490, 1091-6490
On-line přístup:	Zjistit podrobnosti o přístupu
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