Do diabetes and depressed mood affect associations between obesity and quality of life in postmenopause? Results of the KORA-F3 Augsburg population study

Background To assess associations of obesity with health-related quality of life (HRQL) in postmenopausal women, and whether depressed mood and diabetes moderate these associations. Methods Survey of 983 postmenopausal women aged 35-74, general population, Augsburg region/Germany, 2004/2005. Body we...

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Bibliographic Details
Published in:Health and quality of life outcomes Vol. 9; no. 1; p. 97
Main Authors: Heidelberg, Daniela A, Holle, Rolf, Lacruz, Maria E, Ladwig, Karl-Heinz, von Lengerke, Thomas
Format: Journal Article
Language:English
Published: London BioMed Central 04.11.2011
BioMed Central Ltd
Springer Nature B.V
BMC
Subjects:
Adult
Aged
Body weight
Care and treatment
depressed mood
Depression - psychology
Development and progression
Diabetes
diabetes mellitus
Diabetes Mellitus - psychology
Female
Germany
Health aspects
health-related quality of life
Humans
Interviews as Topic
Linear Models
Medical research
Medicine
Medicine & Public Health
Menopause
Middle Aged
Obesity
Obesity - psychology
Physical Examination
Population studies
Postmenopausal women
postmenopause
Postmenopause - psychology
Quality of Life
Quality of Life Research
Risk factors
Studies
Surveys and Questionnaires
Womens health
Germany
health-related quality of life
diabetes mellitus
postmenopause
depressed mood
obesity
ISSN:1477-7525, 1477-7525
Online Access:Get full text
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Summary:Background To assess associations of obesity with health-related quality of life (HRQL) in postmenopausal women, and whether depressed mood and diabetes moderate these associations. Methods Survey of 983 postmenopausal women aged 35-74, general population, Augsburg region/Germany, 2004/2005. Body weight/height and waist/hip circumference were assessed anthropometrically and classified via BMI ≥ 30 as obese, and WHR ≥ 0.85 as abdominally obese (vs. not). Depressed mood was assessed by the Depression and Exhaustion-(DEEX-)scale, diabetes and postmenopausal status by self-report/medication, and HRQL by the SF-12. Results General linear models revealed negative associations of obesity and abdominal obesity with physical but not mental HRQL. Both forms of excess weight were associated with diabetes but not depressed mood. Moderation depended on the HRQL-domain in question. In non-diabetic women, depressed mood was found to amplify obesity-associated impairment in physical HRQL (mean "obese"-"non-obese" difference given depressed mood: -6.4, p < .001; among those without depressed mood: -2.5, p = .003). Reduced mental HRQL tended to be associated with obesity in diabetic women (mean "obese"-"non-obese" difference: -4.5, p = .073), independent of depressed mood. No interactions pertained to abdominal obesity. Conclusions In postmenopausal women, depressed mood may amplify the negative impact of obesity on physical HRQL, while diabetes may be a precondition for some degree of obesity-related impairments in mental HRQL.
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ISSN:1477-7525
1477-7525
DOI:10.1186/1477-7525-9-97