Transfusion-related acute lung injury: a clinical review

Three decades ago, transfusion-related acute lung injury (TRALI) was considered a rare complication of transfusion medicine. Nowadays, the US Food and Drug Administration acknowledge the syndrome as the leading cause of transfusion-related mortality. Understanding of the pathogenesis of TRALI has re...

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 382; no. 9896; pp. 984 - 994
Main Authors:	Vlaar, Alexander PJ, Juffermans, Nicole P
Format:	Journal Article
Language:	English
Published:	Kidlington Elsevier Ltd 14.09.2013 Elsevier Elsevier Limited
Subjects:	Acute Lung Injury - diagnosis Acute Lung Injury - etiology Antibody Formation - physiology Biological and medical sciences Blood platelets Blood transfusions Cytokines Cytokines - metabolism Food and Drug Administration General aspects Humans Internal Medicine Lungs Medical sciences medicine Mortality Neutrophil Activation - immunology Neutrophil Activation - physiology Neutrophils - immunology Pathogenesis Patients physicians Pulmonary Edema - etiology Risk factors Sepsis Studies Surgery Time Factors Transfusion Transfusion Reaction United States Ventilators United States Medicine Review Transfusion related acute lung injury Bibliographic review
ISSN:	0140-6736, 1474-547X, 1474-547X
Online Access:	Get full text
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